Infrastructure

There is extensive research infrastructure available in the capital region to support neuroscience research. This infrastructure comprises services from molecular genetics and cellular models and assays, all the way to advanced neuroimaging facilities and clinical research support.

Below you will find the infrastructures available at the University of Helsinki, Aalto University and HUS Helsinki University Hospital. By selecting the service, you will reach the service website for more information and contact details.

Most services are available for all researchers and clinicians at the University of Helsinki, Aalto University and HUS Helsinki University Hospital, as well as other non-commercial and commercial organisations. You can easily see the availability of the service from these signs:

(A) Open for all users

(R) Access restricted to certain groups

Genetics, Genomics & Gene Technology

AAV Core Unit
UH, Meilahti (R)
Adeno-associated virus (AAV) design and production.


Biomedicum Functional Genomics Unit
UH, Meilahti (A)
NGS transcriptomics, NGS genomics, targeted NGS gene panels, NGS-based genotyping, targeted gene expression analyses, targeted protein assays, RNA and DNA QC analyses, bioinformatics.


DNA Sequencing and Genomics Laboratory (BIDGEN)
UH, Viikki (A)
RNAseq, miRNAseq, Single-cell gene expression and genomics, WGS, amplicons, metagenomics, de novo genome sequencing and assembly, bioinformatics, Sanger sequencing, fragment analysis, high-throughput sequencing.


FIMM Genomics
UH, Meilahti (A)
Sanger sequencing, tailored NGS sequencing, NGS transcriptomics, targeted/ genome-wide genotyping, DNA methylation analysis, cell line authentication.


FIMM HiPrep
UH, Meilahti (A)
RNA isolation and preparation services; workflows for preparation of high-quality nucleic acids from biological samples.


Genome Biology Unit
UH, Meilahti (R)
Gateway cloning, clone libraries, digital slide scanning (high throughout, fluorescent & brightfield). Library clones provided only for Biocenter Finland research groups, scanning and cloning for all customers.

Cell Biology & Cellular Analytics

Biocenter Flow Cytometry
UH, Viikki (A)
Flow cytometry.


Biocomplex Purification
UH, Viikki (A)
Macromolecular sample (e.g. vesicles, viruses, ribonucleoprotein complexes, filaments) preparation and purification; ultracentrifugation, flow field-flow fractionation, chromatography, training, project planning and execution.


Biomedicum Flow Cytometry
UH, Meilahti (A)
Flow cytometry.


Biomedicum Stem Cell Center (BSCC)
UH, Meilahti (A)
Cell and reporter lines (hESCs, hiPSCs), knockout hPSC lines, derivation & characterisation of hiPSC lines, continuous live-cell imaging, training.


CryoEM
UH, Viikki (A)
CryoEM (cryogenic electron microscopy) services and applications.


Crystallization
UH, Viikki (A)
Macromolecular crystallization and X-ray crystallography services and analysis for high resolution structural biology studies.


Extracellular Vesicles Core
UH, Meilahti (A)
Extracellular vesicle isolation and analytics.


Finnish Biological NMR Center
UH, Viikki (A)
Nuclear magnetic resonance (NMR) services and applications.


Neuronal Cell Culture Unit
UH, Meilahti (R)
Primary neuronal cell cultures and training. The service is primarily open for Neurocenter and other academic research groups.


Neuroprotection and Neurorepair Custom Services
UH, Meilahti/Viikki (A)
In vivo and in vitro models of neurodegeneration, consulting and experiment desing, custom-made experiments, data analysis, research reports.


Single-Cell Analytics, FIMM
UH, Meilahti (A)
Various single-cell analytics, e.g. gene espression, immune profiling, ATAC, feature barcoding, taranscriptomics, SNV & CNV analysis and multi-omics.


Single-Cell Proteomics & Genomics, BI
UH, Viikki (A)
Single-cell preparation and processing, Illumina library preparation, single cell transcriptome & proteome readout analysis.


Viikki Sorting Flow Cytometry
UH, Viikki (A)
Fluorescence cell sorter.

Metabolomics, Protein Studies & Drug Discovery

Crystallization
UH, Viikki (A)
Macromolecular crystallization and X-ray crystallography services and analysis for high resolution structural biology studies.


Drug Discovery & Chemical Biology Consortium (DDCB)
National, various locations (A)
National network of sevice providers. Services include drug discovery & chemical biology, assay development, high throughput & high content screening, virtual screening, molecular modeling, chemoinformatics and ADMET studies.


FIMM High Throughput Biomedicine Unit
UH, Meilahti (A)
Various services, such as drug sensitivity and resistance testing, siRNA screening, cell- and biochemical screening, chemical compound libraries, biological profiling, molecular probe discovery.


FIMM Metabolomics/Lipidomics/Fluxomics Unit
UH, Meilahti (A)
High-throuhgput mass spectromety-based metabolomics/lipidomics and fluxomics, data analysis.


Finnish Biological NMR Center
UH, Viikki (A)
Nuclear magnetic resonance (NMR) services and applications.


Helsinki University Lipidomics Unit (HiLIPID)
UH, Viikki (A)
Mass spectrometry-based analysis of lipids, fatty acids and lipid mediators.


Meilahti Clinical Proteomics Core Facility
UH, Meilahti (A)
Proteomics, glycoproteomics, mass spectrometry, protein purification & identification.


Proteomics Unit Viikki
UH, Viikki (A)
Mass spectrometry, protein quantification, protein identification, data analysis.


Viikki Metabolomics Unit
UH, Viikki (A)
Targeted and non-targeted metabolomics.

Microscopy & Histopathology

BI Histoscanner
UH, Viikki (A)
BI Histoscanner, Institute of Biotechnology, offers high throughput, bright field slide scanning service with 3D HISTECH Scanner (20x, 40x objectives), allowing easy, fast and high-quality analysis of digitized slides.


Biomedicum Imaging Unit
UH, Meilahti (A)
Light microscopy and image analysis.


CryoEM
UH, Viikki (A)
CryoEM (cryogenic electron microscopy) services and applications.


Electron Microscopy Institute of Biotechnology (EMBI)
UH, Viikki (A)
Electron microscopy


FIMM Digital Microscopy and Molecular Pathology Unit
UH, Meilahti (A)
High-throughput whole-slide scanning, image analysis, tissue processing, staining.


FIMM High Content Imaging and Analysis (FIMM-HCA)
UH, Meilahti (A)
High-content and high-throughput imaging and image analysis. Laser-capture microdissection from histological sections and cell culture (Leica LMD7), Computer-assisted microscopy isolation of single cells (CAMI).


Finnish Centre for Laboratory Animal Pathology (FCLAP)
UH, Viikki (A)
Histotechnical services, pathology assessment in laboratory animals.


Genome Biology Unit
UH, Meilahti (R)
Gateway cloning, clone libraries, digital slide scanning (high throughput, fluorescent & brightfield). Library clones provided only for Biocenter Finland research groups, scanning and cloning for all customers.


Histology Core Facility
UH, Viikki (A)
Self service and service by a technician. Tissue processing (incl. paraffin embedding), sectioning (incl. microtome, cryostat, vibratome), histological staining, training.


Light Microscopy Unit
UH, Viikki (A)
Light microscopy and image analysis.


Tissue Preparation and Histochemistry Unit
UH, Meilahti (A)
Tissue processing, including cryosectioning, immunohistochemical staining, in-situ hybridization, paraffin sectioning.


Zeiss PALM MicroBeam Laser Microdissection Instrument
UH, Viikki (A)
Laser-capture microdissection from histological sections and cell culture.

Neuroimaging (Human Subjects)

Aalto Neuroimaging (ANI)
Aalto, Otaniemi (A)
Aalto NeuroImaging (ANI) is comprised of four units:
i) Advanced Magnetic Imaging Centre (AMI; fMRI/MRI);
ii) MEG Core (MEG);
iii) Aalto Behavioral Laboratory (ABL; multiple devices for behavioural assays);
iv) Aalto Transcranial Magnetic Stimulation (Aalto TMS; nTMS/rTMS).


Baba Center
UH, Meilahti (R)
Methods for studying baby brain activity using a wide range of behavioral and imaging techniques, such as electroencephalography (EEG). Belongs to HiLIFE infrastucture CoBra.
Access assessed on case-by-case basis.


BioMag
Aalto/ HUS/ UH, Meilahti (A)
Magnetoencephalography (MEG), magnetocardiography (MCG), electroencephalography (EEG), navigated transcranial magnetic stimulation (TMS) and near-infrared spectroscopic imaging (NIRSI). Belongs to HiLIFE infrastucture CoBra.


Cognitive Brain Research Unit
UH, Meilahti (R)
Electroencephalography (EEG) devices, a navigated transcranial magnetic stimulation (TMS) device, behavioral testing space and devices for analyzing autonomous nervous system activity and eye movements. Additionally, various neurocognitive test batteries for children, adolescents and adults, as well as digital questionnaire tools. Belongs to HiLIFE infrastructure CoBra.
Currently access primarily for those with existing experience and skills of using the setup. Access of other users assessed on a case-by-case basis.


HUS Medical Imaging Center
HUS/ UH, Meilahti (R)
Various types of imaging facilities, including magnetic resonance imaging (MRI), computed tomography (CT), ultrasound (US), conventional X-ray, single-photon emission computed tomography/CT (SPECT/CT), positron emission tomography -computed tomography (PET/CT), electroencephalography (EEG), Electromyoneurography (ENMG).
Access assessed on a case-by-case basis.

In Vivo Models & Imaging

Awake Rodent Research Platform
UH, Meilahti (A)
Optical imaging and electrophysiology of the brain and spinal cord in anesthetized or awake freely moving rodents.


Biochemical Analysis Core for Experimental Research
UH, Meilahti (A)
Analysis of laboratory animal blood and urine samples.


Biomedicum Imaging Unit – IVI
UH, Meilahti (A)
Whole-body optical small animal imaging, in vivo microCT analysis and intravital multiphoton microscopy


Diagnostic Imaging Service for Animals
UH, Viikki (A)
Diagnistig imaging services incl. radiohraphy, ultrasonography, CT and MRI.


Genetically Modified Rodents
UH, Viikki (A)
Generation of transgenic rodents, rat cryopreservation and rederivation, DNA pronuclear and CRISPR/Cas9 genome editing methods.


HI-FLY
Uh, Viikki (R)
Drosophila research services, fly food, information regaring fly stock collections.
Access for researchers at UH.


HUS Medical Imaging Center
HUS/UH, Meilahti (R)
Various types of imaging facilities, including magnetic resonance imaging (MRI), computed tomography (CT), ultrasound (US), conventional X-ray, single-photon emission computed tomography/CT (SPECT/CT), positron emission tomography -computed tomography (PET/CT), electroencephalography (EEG), Electromyoneurography (ENMG).
Access assessed on a case-by-case basis.


Laboratory Animal Center (LAC)
UH, Meilahti/ Viikki (A)
Production and maintenance of laboratory animals; animal facilities for e.g. mice, rats, rabbits, hamsters, guinea pigs, sheep, swine, poultry; assistance of researchers.


MicroCT Laboratory
UH, Kumpula (A)
X-ray micro-imaging services, micro-CT, 3D image analysis and visualisation.


Mouse Behavioural Phenotyping (MBPF)
UH, Viikki (R)
A range of mouse phenotyping methods, including behaviour, cognition, learning, motor- and sensory systems, hearing, vision, stress, etc. The service is open for all researchers but animal transfer regulations may cause restrictions for use outside of UH.


Neuroprotection and Neurorepair Custom Services
UH, Meilahti/ Viikki (A)
In vivo and in vitro models of neurodegeneration, consulting and experiment design, custom-made experiments, data analysis, research reports.


Radiopharmaceutical Chemistry
UH, Kumpula (A)
Radiopharmaceuticals for diagnostics and drug discovery, radiotracers for in vitro and in vivo.


Rodent Behavioural Facility
UH, Meilahti (A)
Behavioural and physical characterisation of rodents, incl. locomotor activity, motor coordination and sensory, emotional and cognitive functions.


SPECT-CT Imaging Unit
UH, Viikki (A)
High resolution detection of radioactive tracers in small animals. Quantitation of specific neurotransmitter receptor levels; blood-brain-barrier diffusion capabilities, brain, blood and glymphatic vasculature integrity. Treatment evaluation on disease models: brain ischemia (stroke), dopaminergic denervation (Parkinson’s), neuroinflammation. Whole body tracer biodistribution, elimination and its kinetics.


Zebrafish Unit
Uh, Meilahti (A)
Zebrafish production and maintenance, genetic modification, imaging facilities (live/fixed)

Biobanks & Clinical Research

Canine Biobank
UH, Meilahti (A)
> 80 000 EDTA-blood samples from 330 breeds of dog; hundreds of tissue samples.


Clinical Research Institute HUCH
HUS (R)
Clinical Research Institute HUCH (CRI) is 100 % owned by Helsinki Uusimaa Joint Authority Area. CRI provide research service management for clinical trials performed at HUS, and where the study is sponsored by an external party (i.e. pharmaceutical company or University / University Hospital from another country). The available CRI services include e.g. study budget preparation and negotiations, Clinical Trial Agreement (CTA) negotiations, financial transactions & accounting services, and study monitoring in academic trials for clinical trials at HUS.


Feline Biobank
UH, Meilahti (A)
> 5 000 EDTA-blood samples from about 40 breeds of cat.


FIMM Sample Storage
UH, Meilahti (A)
Storage of samples in liquid nitrogen vapor phase at -180 °C, or in freezers at -20 °C or -80 °C.


Helsinki Biobank
Meilahti campus (A)
Biological samples, sample images, sample-derived data and clinical data.


HUS Diagnostic Center and HUS Pharmacy
HUS (R)
HUS Diagnostic Center includes HUSLAB and HUS Imaging. HUSLAB provides solutions used in research (e.g. buffers, media, etc.). HUS Imaging assists when the research requires patient imaging. HUS Pharmacy provides researchers with pharmaceutical services for clinical trials. HUSLab serves researchers at HUS and UH. HUS Pharmacy service is for clinical trials at HUS.


HUS Electronic Services
HUS (R)
Researcher’s work desk, HUSeCRF, REDCapans HUS DATA lake.


Research Nurse Network
HUS (R)
Research nurse for clinical research. Service for clinical research in HUS.

Engineering & Technology

Aalto Acoustics Lab
Aalto, Otaniemi (R)
Audio processing, spatial sound technologies.
Contact for access queries.


Aalto Electronics ICT
Aalto, Otaniemi (R)
Electromagnetics and material studies, electronic circuit desing and microelectronics, radio science and engineering, and space science and technology. Contact for access queries.


Bioeconomy Infrastructure
Aalto/ VTT, Otaniemi (A)
Development of chemicals, fuels and other materials from renewable biomass utilising biotechnical, chemical, thermal and catalytic processing technologies. Equipment for pretreatment, analysis, characterisation, processing and testing of biobased materials. The infrastructure is co-hosted by Aalto and VTT.


OtaNano
Aalto, Otaniemi (A)
Manufacturing processes and equipment for micro- and nanostructures.


Raw Materials Research Infrastructure (RAMI)
Aalto/ GTK/ VTT, Otaniemi (A)
Inorganic material research, spectroscopy, electrochemistry, chromatography. The infrastructure is co-hosted by Aalto, GTK and VTT. Another RAMI website.

IT, Bioinformatics & Biostatistics

Biostatistics Unit
UH, Meilahti (R)
Statistical consultation, e.g. advising on planning research (preferable stage for contacting statistician) and analysis, performing analysis, interpreting and reporting results, power calculations and software. The service is primarily targeted to researchers and research groups at The Faculty of Medicine at the University of Helsinki, HUCH and FIMM.


FIMM IT
UH, Meilahti (A)
Informatics infrastructure for solving questions in bioinformatics, biobanking, molecular medicine, genetics and related fields. Services include e.g. sample logistics, data collection, data production and management, analysis pipelines and data integration.


Science-IT
Aalto, Otaniemi (R)
Computational research, provide Triton cluster (high performance computing) and data storage. Access primarily for academic groups. Companies are welcome to enquire.


Viikki Bi Bioinformatics
UH, Viikki (A)
Data analysis and web services, RNAseq analysis, genome annotation.

Other

Aalto Industry and Innovation Infrastructure
Aalto, Otaniemi (A)
Prototyping, product development.


Playful Learning Center
UH, Center (A)
A space for designing, developing and evaluating playful learning methods, environments and tools. Testing of device and interface prototypes and learning environments.
Access primarily for researchers at the Faculty of Educational Sciences but others are welcome to enquire.


Proofreading Service
UH, Viikki (R)
Proofreading of work written in non-native language.
Access for UH researchers and those with dual employment in HUS & UH.


Research Funding Service
HUS/ UH (R)
Support in research funding applications; information and training. For advice on research projects at HUS, you can contact tutkimusneuvonta@hus.fi directly.
Access for researchers at HUS and UH.


Research Infrastructure for Psychology and Logopedics (RIPL)
UH, Meilahti (R)
Research facilities for behavioral, logopedic, neuropsychological, and neurophysiological measurements/testing of a humans, including test and analysis equipment and supporting staff.
Contact for access queries.

Contact

Anne Patana
Head of Development Helsinki Brain & Mind, University of Helsinki
anne.patana@helsinki.fi
+358505913279

helsinkibrainandmind@helsinki.fi